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How long after applying Retin A can I apply moisturizer? My preferred method is to apply the Retin -A on bare skin, at least 20 minutes after washing, and then wait another 45 minutes before applying moisturizer (or a face oil) on top. The reason for this is that you want to let the Retin -A penetrate for as long as possible before diluting its benefits with another product.
How much retinol should you use? The Best Skin Care Products to Use With Retinol Subjects cleansed with AHAs and then applied a retinol -based anti-aging serum twice a day (in addition to SPF 50+), which proved to be safe and effective for skin with moderate-to-severe photo damage.